A Multi-Institutional Experience in Pediatric High-Grade Glioma
نویسندگان
چکیده
منابع مشابه
A Multi-Institutional Experience in Pediatric High-Grade Glioma
INTRODUCTION Pediatric high-grade gliomas are rare tumors with poor outcomes and incompletely defined management. We conducted a multi-institutional retrospective study to evaluate association of clinical, pathologic, and treatment characteristics with outcomes. MATERIALS AND METHODS Fifty-one patients treated from 1984 to 2008 at the Ohio State University or University of Michigan were inclu...
متن کاملCommentary on: “A Multi-Institutional Experience in Pediatric High Grade Glioma”
This multi-institutional retrospective study evaluates the association of clinical, pathological, and treatment characteristics with their outcomes. Their results show total resection and receiving chemotherapy adjuvant to radiation or chemoradiation are most strongly related with improved progression-free survival (PFS) and overall survival. For higher risk incompletely resected patients, temo...
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Pediatric central nervous system tumors are the most common solid tumor of childhood. Of these, approximately one-third are gliomas that exhibit diverse biological behaviors in the unique context of the developing nervous system. Although low-grade gliomas predominate and have favorable outcomes, up to 20% of pediatric gliomas are high-grade. These tumors are a major contributor to cancer-relat...
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ژورنال
عنوان ژورنال: Frontiers in Oncology
سال: 2015
ISSN: 2234-943X
DOI: 10.3389/fonc.2015.00028